High-Dose Radioembolization Limited by Lung Shunt for HCC Supplied by IPA

High-Dose Radioembolization Limited by Lung Shunt for Hepatocellular Carcinoma Supplied by the Inferior Phrenic Artery

🔍 **Clinical Question:**  

Is radioembolization with lung-shunt limited high dose safe and effective via the inferior phrenic artery (IPA) supplying hepatocellular carcinoma (HCC)?

💡 **Key Insight:**  

Radioembolization via the inferior phrenic artery was performed with acceptable toxicity in 43 of 44 patients with single nodular or oligonodular hepatocellular carcinoma of 4–12 cm in diameter.

The complete response rate and objective response rate by 1 session of radioembolization were 44.2% and 97.7%, respectively. The 2-year and 5-year overall survival rates were 83.9% and 70.9%, respectively.

👉 **Why it matters:**  

Radioembolization with lung-shunt limited high dose can be performed with acceptable toxicity in patients with HCC supplied by the IPA.

➡️ **Full Article:**

brnw.ch... #InterventionalRadiology #IO #Y90 #HCC #MedEd

MRI-guided TULSA of Localized Prostate Cancer Thibault Tricard

Magnetic Resonance Imaging-guided Transurethral Ultrasound Ablation (TULSA) of Localized Prostate Cancer: A prospective Trial

🔍 **Clinical Question:**  

Is the TULSA-PRO device safe and effective in treating organ-confined low-risk to intermediate-risk prostate cancer (PCa)

💡 **Key Insight:**  

After 12 months, 43.5% of patients still had a biopsy-detectable cancerous tumor. However, there was a 40% recurrence-free rate and a 72% treatment-free survival rate at a median follow-up of 37 months.

Urinary and sexual dysfunction was common, with 26% developing stress incontinence, 35% developing overactive bladder, and 54% of potent patients developing erectile dysfunction.

👉 **Why it matters:**  

The TULSA-PRO device shows promising results for the focal treatment of localized prostate cancer, although it is not universally curative and was associated with urinary and sexual functional deficits.

➡️ **Full Article:** 

https://brnw.ch/21wVBIy

#InterventionalRadiology #IO #Ablation #ProstateCancer #MedEd

PAVM Transarterial Embolization - Meta Analysis

Transarterial Embolization for Pulmonary Arteriovenous Malformation: A Systematic Review and Meta-Analysis 

🔍 **Clinical Question:** 

Does an updated meta-analysis continue to show that transcatheter embolization for treatment of pulmonary arteriovenous malformations (PAVMs) is safe and effective? What additional insights does it offer? 

💡 **Key Insight:** 

Transcatheter embolization for pulmonary arteriovenous malformations demonstrated a high technical success rate (>98%), whereas the reported rate of postembolization catastrophic events was low (1.0%). The use of vascular plugs was associated with significantly lower persistence rates than coils only (13.6% vs 32.7%). 

Venous sac embolization showed a markedly lower persistence rate than feeding artery embolization (3.8% vs 24.3%). 

👉 **Why it matters:** 

PAVM embolization, especially using vascular plugs and encompassing venous sac embolization, has favorable technical and treatment success rates and low risk of severe AEs. 

➡️ **Full Article:** 

brnw.ch... 

#InterventionalRadiology #pAVM #HHT #Meta-Analysis #MedEd